The Louisville Cardinals and the Purdue Boilermakers will open the 2017 season at Lucas Oil Stadium in Indianapolis, according to an ESPN report.
Louisville and Purdue are slated to meet on Sept. 2, 2017. The two schools have only met once on the gridiron, a 1987 matchup in West Lafayette, Indiana that ended in a 22-22 tie.
Louisville has one other non-conference game scheduled in 2017 — their season finale at in-state rival Kentucky on Nov. 25.
Purdue also has one other non-conference matchup in 2017, a Sept. 16 trip to take on the Missouri Tigers in Columbia.
The addition of the Louisville-Purdue game would bring the total number of opening weekend neutral-site games to five in 2017. Other games scheduled are BYU vs. LSU (at Houston, TX), Colorado vs. Colorado State (Denver, CO), Florida vs. Michigan (at Arlington, TX), and West Virginia vs. Virginia Tech (at Landover, MD).