 | Louisville Cardinals | |
2008 Louisville Cardinals Football ScheduleFinal Record: 5-7, 1-6 (Big East) | ||||
| Date | Opponent | Result | Tickets | |
| Sunday Aug. 31 |  | Kentucky Wildcats Papa John's Cardinal Stadium, Louisville, KY | Lost 27-2 | --- |
| Saturday Sept. 6 |  | Tennessee Tech Golden Eagles Papa John's Cardinal Stadium, Louisville, KY | Won 51-10 | --- |
| Saturday Sept. 13 | --- | Open Date | --- | --- |
| Wednesday Sept. 17 |  | Kansas State Wildcats Papa John's Cardinal Stadium, Louisville, KY | Won 38-29 | --- |
| Friday Sept. 26 |  | Connecticut Huskies Papa John's Cardinal Stadium, Louisville, KY | Lost 26-21 | --- |
| Saturday Oct. 4 | --- | Open Date | --- | --- |
| Friday Oct. 10 |  | at Memphis Tigers Liberty Bowl Memorial Stadium, Memphis, TN | Won 35-28 | --- |
| Saturday Oct. 18 |  | Middle Tennessee Blue Raiders Papa John's Cardinal Stadium, Louisville, KY | Won 42-23 | --- |
| Saturday Oct. 25 |  | USF Bulls Papa John's Cardinal Stadium, Louisville, KY | Won 24-20 | --- |
| Saturday Nov. 1 |  | at Syracuse Orange Carrier Dome, Syracuse, NY | Lost 28-21 | --- |
| Saturday Nov. 8 |  | at Pittsburgh Panthers Heinz Field, Pittsburgh, PA | Lost 41-7 | --- |
| Friday Nov. 14 |  | Cincinnati Bearcats Papa John's Cardinal Stadium, Louisville, KY | Lost 28-20 | --- |
| Saturday Nov. 22 |  | West Virginia Mountaineers Papa John's Cardinal Stadium, Louisville, KY | Lost 35-21 | --- |
| Saturday Nov. 29 | --- | Open Date | --- | --- |
| Thursday Dec. 4 |  | at Rutgers Scarlet Knights Rutgers Stadium, Piscataway, NJ | Lost 63-14 | --- |
