 | Wyoming Cowboys | |
| 2008 Wyoming Cowboys Football Schedule Final Record: 4-8, 1-7 (MWC) | ||||
| Date | Opponent | Result | Tickets | |
| Saturday Aug. 30 |  | Ohio Bobcats War Memorial Stadium, Laramie, WY | Won 21-20 | --- |
| Saturday Sept. 6 |  | Air Force Falcons War Memorial Stadium, Laramie, WY | Lost 23-9 | --- |
| Saturday Sept. 13 |  | North Dakota State Bison War Memorial Stadium, Laramie, WY | Won 16-13 | --- |
| Saturday Sept. 20 |  | at BYU Cougars LaVell Edwards Stadium, Provo, UT | Lost 44-0 | --- |
| Saturday Sept. 27 |  | Bowling Green Falcons War Memorial Stadium, Laramie, WY | Lost 45-16 | --- |
| Saturday Oct. 4 |  | at New Mexico Lobos University Stadium, Albuquerque, NM | Lost 24-0 | --- |
| Saturday Oct. 11 |  | Utah Utes War Memorial Stadium, Laramie, WY | Lost 40-7 | --- |
| Saturday Oct. 18 | --- | Open Date | --- | --- |
| Saturday Oct. 25 |  | at TCU Horned Frogs Amon G. Carter Stadium, Fort Worth, TX | Lost 54-7 | --- |
| Saturday Nov. 1 |  | San Diego State Aztecs War Memorial Stadium, Laramie, WY | Won 35-10 | --- |
| Saturday Nov. 8 |  | at Tennessee Volunteers Neyland Stadium, Knoxville, TN | Won 13-7 | --- |
| Thursday Nov. 13 |  | at UNLV Rebels Sam Boyd Stadium, Las Vegas, NV | Lost 22-14 | --- |
| Saturday Nov. 22 |  | Colorado State Rams War Memorial Stadium, Laramie, WY | Lost 31-20 | --- |
