 | Clemson Tigers | |
2010 Clemson Tigers Football ScheduleFinal Record: 6-7, 4-4 (ACC) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 3:30 p.m. ET |  North Texas | Won 35-10 | --- |
| Sat. Sept. 11 3:30 p.m. ET |  Presbyterian | Won 58-21 | --- |
| Sat. Sept. 18 7:00 p.m. ET |  at Auburn | Lost 27-24 (OT) | --- |
| Sat. Sept. 25 | Open Date | --- | --- |
| Sat. Oct. 2 12:00 p.m. ET |  Miami (FL) | Lost 30-21 | --- |
| Sat. Oct. 9 3:30 p.m. ET |  at North Carolina | Lost 21-16 | --- |
| Sat. Oct. 16 12:00 p.m. ET |  Maryland | Won 31-7 | --- |
| Sat. Oct. 23 3:30 p.m. ET |  Georgia Tech | Won 27-13 | --- |
| Sat. Oct. 30 12:00 p.m. ET |  at Boston College | Lost 16-10 | --- |
| Sat. Nov. 6 12:00 p.m. ET |  NC State | Won 14-13 | --- |
| Sat. Nov. 13 8:00 p.m. ET |  at Florida State | Lost 16-13 | --- |
| Sat. Nov. 20 2:00 p.m. ET |  at Wake Forest | Won 30-10 | --- |
| Sat. Nov. 27 7:00 p.m. ET |  South Carolina | Lost 29-7 | --- |
| 2010 Meineke Car Care Bowl at Charlotte, NC (Bank of America Stadium) | |||
| Fri. Dec. 31 12:00 p.m. ET |  USF | Lost 31-26 | --- |
