 | Duke Blue Devils | |
2010 Duke Blue Devils Football ScheduleFinal Record: 3-9, 1-7 (ACC) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 7:00 p.m. ET |  Elon | Won 41-27 | --- |
| Sat. Sept. 11 12:00 p.m. ET |  at Wake Forest | Lost 54-48 | --- |
| Sat. Sept. 18 3:30 p.m. ET |  Alabama | Lost 62-13 | --- |
| Sat. Sept. 25 3:00 p.m. ET |  Army | Lost 35-21 | --- |
| Sat. Oct. 2 6:00 p.m. ET |  at Maryland | Lost 21-16 | --- |
| Sat. Oct. 9 | Open Date | --- | --- |
| Sat. Oct. 16 1:00 p.m. ET |  Miami (FL) | Lost 28-13 | --- |
| Sat. Oct. 23 12:00 p.m. ET |  at Virginia Tech | Lost 44-7 | --- |
| Sat. Oct. 30 3:30 p.m. ET |  at Navy | Won 34-31 | --- |
| Sat. Nov. 6 12:00 p.m. ET |  Virginia | Won 55-48 | --- |
| Sat. Nov. 13 12:00 p.m. ET |  Boston College | Lost 21-16 | --- |
| Sat. Nov. 20 1:30 p.m. ET |  at Georgia Tech | Lost 30-20 | --- |
| Sat. Nov. 27 3:30 p.m. ET |  North Carolina | Lost 24-19 | --- |
