 | Louisville Cardinals | |
2010 Louisville Cardinals Football ScheduleFinal Record: 7-6, 3-4 (Big East) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 3:30 p.m. ET |  Kentucky | Lost 23-16 | --- |
| Sat. Sept. 11 3:30 p.m. ET |  Eastern Kentucky | Won 23-13 | --- |
| Sat. Sept. 18 5:35 p.m. ET |  at Oregon State | Lost 35-28 | --- |
| Sat. Sept. 25 | Open Date | --- | --- |
| Sat. Oct. 2 7:00 p.m. ET |  at Arkansas State | Won 34-24 | --- |
| Sat. Oct. 9 2:00 p.m. ET |  Memphis | Won 56-0 | --- |
| Fri. Oct. 15 8:00 p.m. ET |  Cincinnati | Lost 35-27 | --- |
| Sat. Oct. 23 3:30 p.m. ET |  Connecticut | Won 26-0 | --- |
| Sat. Oct. 30 12:00 p.m. ET |  at Pittsburgh | Lost 20-3 | --- |
| Sat. Nov. 6 12:00 p.m. ET |  at Syracuse | Won 28-20 | --- |
| Sat. Nov. 13 12:00 p.m. ET |  USF | Lost 24-21 (OT) | --- |
| Sat. Nov. 20 12:00 p.m. ET |  West Virginia | Lost 17-10 | --- |
| Fri. Nov. 26 11:00 a.m. ET |  at Rutgers | Won 40-13 | --- |
| 2010 Beef 'O' Brady's Bowl at St. Petersburg, FL (Tropicana Field) | |||
| Tue. Dec. 21 8:00 p.m. ET |  Southern Miss | Won 31-28 | --- |
