 | South Florida Bulls | |
2010 USF Bulls Football ScheduleFinal Record: 8-5, 3-4 (Big East) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 7:05 p.m. ET |  Stony Brook | Won 59-14 | --- |
| Sat. Sept. 11 12:20 p.m. ET |  at Florida | Lost 38-14 | --- |
| Sat. Sept. 18 | Open Date | --- | --- |
| Sat. Sept. 25 7:05 p.m. ET |  Western Kentucky | Won 24-12 | --- |
| Sat. Oct. 2 7:05 p.m. ET |  Florida Atlantic | Won 31-3 | --- |
| Sat. Oct. 9 12:00 p.m. ET |  Syracuse | Lost 13-9 | --- |
| Thu. Oct. 14 7:30 p.m. ET |  at West Virginia | Lost 20-6 | --- |
| Fri. Oct. 22 8:00 p.m. ET |  at Cincinnati | Won 38-30 | --- |
| Sat. Oct. 30 | Open Date | --- | --- |
| Wed. Nov. 3 7:00 p.m. ET |  Rutgers | Won 28-27 | --- |
| Sat. Nov. 13 12:00 p.m. ET |  at Louisville | Won 24-21 (OT) | --- |
| Sat. Nov. 20 12:00 p.m. ET |  Pittsburgh | Lost 17-10 | --- |
| Sat. Nov. 27 12:00 p.m. ET |  at Miami (FL) | Won 23-20 (OT) | --- |
| Sat. Dec. 4 8:00 p.m. ET |  Connecticut | Lost 19-16 | --- |
| 2010 Meineke Car Care Bowl at Charlotte, NC (Bank of America Stadium) | |||
| Fri. Dec. 31 12:00 p.m. ET |  Clemson | Won 31-26 | --- |
