 | Purdue Boilermakers | |
2010 Purdue Boilermakers Football ScheduleFinal Record: 4-8, 2-6 (Big Ten) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 3:30 p.m. ET |  at Notre Dame | Lost 23-12 | --- |
| Sat. Sept. 11 12:00 p.m. ET |  Western Illinois | Won 31-21 | --- |
| Sat. Sept. 18 12:00 p.m. ET |  Ball State | Won 24-13 | --- |
| Sat. Sept. 25 12:00 p.m. ET |  Toledo | Lost 31-20 | --- |
| Sat. Oct. 2 | Open Date | --- | --- |
| Sat. Oct. 9 7:30 p.m. ET |  at Northwestern | Won 20-17 | --- |
| Sat. Oct. 16 12:00 p.m. ET |  Minnesota | Won 28-17 | --- |
| Sat. Oct. 23 12:00 p.m. ET |  at Ohio State | Lost 49-0 | --- |
| Sat. Oct. 30 12:00 p.m. ET |  at Illinois | Lost 44-10 | --- |
| Sat. Nov. 6 12:00 p.m. ET |  Wisconsin | Lost 34-13 | --- |
| Sat. Nov. 13 12:00 p.m. ET |  Michigan | Lost 27-16 | --- |
| Sat. Nov. 20 12:00 p.m. ET |  at Michigan State | Lost 35-31 | --- |
| Sat. Nov. 27 12:00 p.m. ET |  Indiana | Lost 34-31 (OT) | --- |
