 | Buffalo Bulls | |
2010 Buffalo Bulls Football ScheduleFinal Record: 2-10, 1-7 (MAC) | |||
| Date/Time | Opponent | Result | Tickets |
| Sat. Sept. 4 7:00 p.m. ET |  Rhode Island | Won 31-0 | --- |
| Sat. Sept. 11 7:00 p.m. ET |  at Baylor | Lost 34-6 | --- |
| Sat. Sept. 18 7:00 p.m. ET |  UCF | Lost 24-10 | --- |
| Sat. Sept. 25 12:00 p.m. ET |  at Connecticut | Lost 45-21 | --- |
| Sat. Oct. 2 3:30 p.m. ET |  at Bowling Green | Won 28-26 | --- |
| Sat. Oct. 9 | Open Date | --- | --- |
| Sat. Oct. 16 3:30 p.m. ET |  at Northern Illinois | Lost 45-14 | --- |
| Sat. Oct. 23 12:00 p.m. ET |  Temple | Lost 42-0 | --- |
| Sat. Oct. 30 3:30 p.m. ET |  Miami (OH) | Lost 21-9 | --- |
| Thu. Nov. 4 7:30 p.m. ET |  at Ohio | Lost 34-17 | --- |
| Fri. Nov. 12 6:00 p.m. ET |  Ball State | Lost 20-3 | --- |
| Sat. Nov. 20 2:00 p.m. ET |  Eastern Michigan | Lost 21-17 | --- |
| Fri. Nov. 26 2:00 p.m. ET |  at Akron | Lost 22-14 | --- |
