2010 Ohio Bobcats Football ScheduleFinal Record: 8-5, 6-2 (MAC) | ||||
| Date | Opponent | Result | Tickets | |
| Saturday Sep. 4 |  | Wofford Terriers Peden Stadium, Athens, OH | Won 33-10 | |
| Saturday Sep. 11 |  | Toledo Rockets Peden Stadium, Athens, OH | Lost 20-13 | |
| Saturday Sep. 18 |  | at Ohio State Buckeyes Ohio Stadium, Columbus, OH | Lost 43-7 | |
| Saturday Sep. 25 |  | at Marshall Thundering Herd Joan C. Edwards Stadium, Huntington, WV | Lost 24-23 | |
| Saturday Oct. 2 |  | at Eastern Michigan Eagles Rynearson Stadium, Ypsilanti, MI | Won 30-17 | |
| Saturday Oct. 9 |  | Bowling Green Falcons Peden Stadium, Athens, OH | Won 49-25 | |
| Saturday Oct. 16 |  | Akron Zips Peden Stadium, Athens, OH | Won 38-10 | |
| Saturday Oct. 23 |  | at Miami (OH) RedHawks Yager Stadium, Oxford, OH | Won 34-13 | |
| Saturday Oct. 30 |  | Louisiana's Ragin' Cajuns Peden Stadium, Athens, OH | Won 38-31 | |
| Thursday Nov. 4 |  | Buffalo Bulls Peden Stadium, Athens, OH | Won 34-17 | |
| Saturday Nov. 13 | Open Date | |||
| Tuesday Nov. 16 |  | at Temple Owls Lincoln Financial Field, Philadelphia, PA | Won 31-23 | |
| Friday Nov. 26 |  | at Kent State Golden Flashes Dix Stadium, Kent, OH | Lost 28-6 | |
| 2010 R+L Carriers New Orleans Bowl | ||||
| Saturday Dec. 18 |  | Troy Trojans Louisiana Superdome, New Orleans, LA | Lost 48-21 | |
