2015 Louisville Cardinals Football ScheduleRecord: 8-5, 5-3 (ACC) |
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| Date | Opponent | Time/TV | Tickets | |
| Saturday Sep. 5 |
 |
Auburn Tigers Georgia Dome, Atlanta, GA |
Lost 31-24 | |
| Saturday Sep. 12 |
 |
Houston Cougars Papa John's Cardinal Stadium, Louisville, KY |
Lost 34-31 | |
| Thursday Sep. 17 |
 |
Clemson Tigers Papa John's Cardinal Stadium, Louisville, KY |
Lost 20-17 | |
| Saturday Sep. 26 |
 |
Samford Bulldogs Papa John's Cardinal Stadium, Louisville, KY |
Won 45-3 | |
| Saturday Oct. 3 |
 |
at NC State Wolfpack Carter-Finley Stadium, Raleigh, NC |
Won 20-13 | |
| Saturday Oct. 10 |
Open Date | |||
| Saturday Oct. 17 |
 |
at Florida State Seminoles Doak Campbell Stadium, Tallahassee, FL |
Lost 41-21 | |
| Saturday Oct. 24 |
 |
Boston College Eagles (HC) Papa John's Cardinal Stadium, Louisville, KY |
Won 17-14 | |
| Friday Oct. 30 |
 |
at Wake Forest Demon Deacons BB&T Field, Winston-Salem, NC |
Won 20-19 | |
| Saturday Nov. 7 |
 |
Syracuse Orange Papa John's Cardinal Stadium, Louisville, KY |
Won 41-17 | |
| Saturday Nov. 14 |
 |
Virginia Cavaliers Papa John's Cardinal Stadium, Louisville, KY |
Won 38-31 | |
| Saturday Nov. 21 |
 |
at Pittsburgh Panthers Heinz Field, Pittsburgh, PA |
Lost 45-34 | |
| Saturday Nov. 28 |
 |
at Kentucky Wildcats Commonwealth Stadium, Lexington, KY |
Won 38-24 | |
| 2015 Franklin American Mortgage Music City Bowl | ||||
| Wednesday Dec. 30 |
 |
Texas A&M Aggies Nissan Stadium, Nashville, TN |
Won 27-21 | |
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