 | Detroit Lions | |
2008 Detroit Lions Football ScheduleFinal Record: 0-16, 0-6 (NFC North) | ||||
| Date | Opponent | Result | Tickets | |
| Sunday Sept. 7 |  | at Atlanta Falcons Georgia Dome, Atlanta, GA | Lost 34-21 | --- |
| Sunday Sept. 14 |  | Green Bay Packers Ford Field, Detroit, MI | Lost 48-25 | --- |
| Sunday Sept. 21 |  | at San Francisco 49ers Candlestick Park, San Francisco, CA | Lost 31-13 | --- |
| Sunday Sept. 28 | --- | BYE | --- | --- |
| Sunday Oct. 5 |  | Chicago Bears Ford Field, Detroit, MI | Lost 34-7 | --- |
| Sunday Oct. 12 |  | at Minnesota Vikings Mall of America Field, Minneapolis, MN | Lost 12-10 | --- |
| Sunday Oct. 19 |  | at Houston Texans Reliant Stadium, Houston, TX | Lost 28-21 | --- |
| Sunday Oct. 26 |  | Washington Redskins Ford Field, Detroit, MI | Lost 25-17 | --- |
| Sunday Nov. 2 | | at Chicago Bears Soldier Field, Chicago, IL | Lost 27-23 | --- |
| Sunday Nov. 9 |  | Jacksonville Jaguars Ford Field, Detroit, MI | Lost 38-14 | --- |
| Sunday Nov. 16 |  | at Carolina Panthers Bank of America Stadium, Charlotte, NC | Lost 31-22 | --- |
| Sunday Nov. 23 |  | Tampa Bay Buccaneers Ford Field, Detroit, MI | Lost 38-20 | --- |
| Thursday Nov. 27 |  | Tennessee Titans Ford Field, Detroit, MI | Lost 47-10 | --- |
| Sunday Dec. 7 | | Minnesota Vikings Ford Field, Detroit, MI | Lost 20-16 | --- |
| Sunday Dec. 14 |  | at Indianapolis Colts Lucas Oil Stadium, Indianapolis, IN | Lost 31-21 | --- |
| Sunday Dec. 21 |  | New Orleans Saints Ford Field, Detroit, MI | Lost 42-7 | --- |
| Sunday Dec. 28 | | at Green Bay Packers Lambeau Field, Green Bay, WI | Lost 31-21 | --- |
