 | St. Louis Rams | |
2008 St. Louis Rams Football ScheduleFinal Record: 2-14, 0-6 (NFC West) | ||||
| Date | Opponent | Result | Tickets | |
| Sunday Sept. 7 |  | at Philadelphia Eagles Lincoln Financial Field, Philadelphia, PA | Lost 38-3 | --- |
| Sunday Sept. 14 |  | New York Giants Edward Jones Dome, St. Louis, MO | Lost 41-13 | --- |
| Sunday Sept. 21 |  | at Seattle Seahawks Qwest Field, Seattle, WA | Lost 37-13 | --- |
| Sunday Sept. 28 |  | Buffalo Bills Edward Jones Dome, St. Louis, MO | Lost 31-14 | --- |
| Sunday Oct. 5 | --- | BYE | --- | --- |
| Sunday Oct. 12 |  | at Washington Redskins FedEx Field, Landover, MD | Won 19-17 | --- |
| Sunday Oct. 19 |  | Dallas Cowboys Edward Jones Dome, St. Louis, MO | Won 34-14 | --- |
| Sunday Oct. 26 |  | at New England Patriots Gillette Stadium, Foxborough, MA | Lost 23-16 | --- |
| Sunday Nov. 2 |  | Arizona Cardinals Edward Jones Dome, St. Louis, MO | Lost 34-13 | --- |
| Sunday Nov. 9 |  | at New York Jets Giants Stadium, East Rutherford, NJ | Lost 47-3 | --- |
| Sunday Nov. 16 |  | at San Francisco 49ers Candlestick Park, San Francisco, CA | Lost 35-16 | --- |
| Sunday Nov. 23 |  | Chicago Bears Edward Jones Dome, St. Louis, MO | Lost 27-3 | --- |
| Sunday Nov. 30 |  | Miami Dolphins Edward Jones Dome, St. Louis, MO | Lost 16-12 | --- |
| Sunday Dec. 7 | | at Arizona Cardinals University of Phoenix Stadium, Glendale, AZ | Lost 34-10 | --- |
| Sunday Dec. 14 | | Seattle Seahawks Edward Jones Dome, St. Louis, MO | Lost 23-20 | --- |
| Sunday Dec. 21 | | San Francisco 49ers Edward Jones Dome, St. Louis, MO | Lost 17-16 | --- |
| Sunday Dec. 28 |  | at Atlanta Falcons Georgia Dome, Atlanta, GA | Lost 31-27 | --- |
