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San Francisco 49ers | |
2010 San Francisco 49ers Football ScheduleFinal Record: 6-10, 4-2 (NFC West) |
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| Date | Opponent | Result | Tickets | |
| Sunday Sept. 12 |
 |
at Seattle Seahawks Qwest Field, Seattle, WA |
Lost 31-6 | --- |
| Monday Sept. 20 |
 |
New Orleans Saints Candlestick Park, San Francisco, CA |
Lost 25-22 | --- |
| Sunday Sept. 26 |
 |
at Kansas City Chiefs Arrowhead Stadium, Kansas City, MO |
Lost 31-10 | --- |
| Sunday Oct. 3 |
 |
at Atlanta Falcons Georgia Dome, Atlanta, GA |
Lost 16-14 | --- |
| Sunday Oct. 10 |
 |
Philadelphia Eagles Candlestick Park, San Francisco, CA |
Lost 27-24 | --- |
| Sunday Oct. 17 |
 |
Oakland Raiders Candlestick Park, San Francisco, CA |
Won 17-9 | --- |
| Sunday Oct. 24 |
 |
at Carolina Panthers Bank of America Stadium, Charlotte, NC |
Lost 23-20 | --- |
| Sunday Oct. 31 |
 |
Denver Broncos Wembley Stadium, London, England, UK |
Won 24-16 | --- |
| Sunday Nov. 7 |
--- | BYE | --- | --- |
| Sunday Nov. 14 |
 |
St. Louis Rams Candlestick Park, San Francisco, CA |
Won 23-20 (OT) |
--- |
| Sunday Nov. 21 |
 |
Tampa Bay Buccaneers Candlestick Park, San Francisco, CA |
Lost 21-0 | --- |
| Monday Nov. 29 |
 |
at Arizona Cardinals University of Phoenix Stadium, Glendale, AZ |
Won 27-6 | --- |
| Sunday Dec. 5 |
 |
at Green Bay Packers Lambeau Field, Green Bay, WI |
Lost 34-16 | --- |
| Sunday Dec. 12 |
|
Seattle Seahawks Candlestick Park, San Francisco, CA |
Won 40-21 | --- |
| Thursday Dec. 16 |
 |
at San Diego Chargers Qualcomm Stadium, San Diego, CA |
Lost 34-7 | --- |
| Sunday Dec. 26 |
|
at St. Louis Rams Edward Jones Dome, St. Louis, MO |
Lost 25-17 | --- |
| Sunday Jan. 2 |
|
Arizona Cardinals Candlestick Park, San Francisco, CA |
Won 38-7 | --- |
