 | Buffalo Bills | |
2012 Buffalo Bills Football Schedule | ||||
| Date | Opponent | Result | Tickets | |
| Sunday Sept. 9 |  | at New York Jets MetLife Stadium, East Rutherford, NJ | Lost 48-28 | --- |
| Sunday Sept. 16 |  | Kansas City Chiefs Ralph Wilson Stadium, Orchard Park, NY | Won 35-17 | --- |
| Sunday Sept. 23 |  | at Cleveland Browns Cleveland Browns Stadium, Cleveland, OH | Won 24-14 | --- |
| Sunday Sept. 30 |  | New England Patriots Ralph Wilson Stadium, Orchard Park, NY | Lost 52-28 | --- |
| Sunday Oct. 7 |  | at San Francisco 49ers Candlestick Park, San Francisco, CA | Lost 45-3 | --- |
| Sunday Oct. 14 |  | at Arizona Cardinals University of Phoenix Stadium, Glendale, AZ | Won 19-16 (OT) | --- |
| Sunday Oct. 21 |  | Tennessee Titans Ralph Wilson Stadium, Orchard Park, NY | Lost 35-34 | --- |
| Sunday Oct. 28 | --- | Open Date | --- | --- |
| Sunday Nov. 4 |  | at Houston Texans Reliant Stadium, Houston, TX | Lost 21-9 | --- |
| Sunday Nov. 11 | | at New England Patriots Gillette Stadium, Foxborough, MA | Lost 37-31 | --- |
| Thursday Nov. 15 |  | Miami Dolphins Ralph Wilson Stadium, Orchard Park, NY | Won 19-14 | --- |
| Sunday Nov. 25 |  | at Indianapolis Colts Lucas Oil Stadium, Indianapolis, IN | Lost 20-13 | --- |
| Sunday Dec. 2 |  | Jacksonville Jaguars Ralph Wilson Stadium, Orchard Park, NY | Won 34-18 | --- |
| Sunday Dec. 9 |  | St. Louis Rams Ralph Wilson Stadium, Orchard Park, NY | Lost 15-12 | --- |
| Sunday Dec. 16 |  | Seattle Seahawks Rogers Centre, Toronto, ON, Canada | Lost 50-17 | --- |
| Sunday Dec. 23 | | at Miami Dolphins Sun Life Stadium, Miami Gardens, FL | Lost 24-10 | --- |
| Sunday Dec. 30 | | New York Jets Ralph Wilson Stadium, Orchard Park, NY | Won 28-9 | --- |
